发明名称 |
Isolated nucleic acid molecules encoding a novel human signal transducing kinase-mapkap-2; encoded proteins, cells transformed therewith and uses thereof |
摘要 |
Disclosed herein are two newly identified enzymes-mitogen-activated protein kinase-activated protein kinase-2, each comprising a sequence of nucleotides as set forth in SEQ ID NOs: 1 and 3. Each of the herein disclosed enzymes is a serine/threonine signal transduction kinase that is phosphorylated and activated by Erks and p38 MAPK in vitro. Also disclosed, inter alia, are cells containing the recombinant nucleic acid molecules; antisense constructs thereto; antibodies specific for each of the disclosed proteins; methods for using the novel nucleic acid molecules and their gene products including kits containing the same.
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申请公布号 |
US2004170995(A1) |
申请公布日期 |
2004.09.02 |
申请号 |
US20040469221 |
申请日期 |
2004.02.11 |
申请人 |
LOGRASSO PHILLIP;HAWKINS JULIO;LISNOCK JEAN MARIE |
发明人 |
LOGRASSO PHILLIP;HAWKINS JULIO;LISNOCK JEAN MARIE |
分类号 |
G01N33/50;A61K38/45;A61P1/04;A61P9/10;A61P11/06;A61P19/02;A61P25/28;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P37/08;C07K16/40;C12N1/21;C12N5/10;C12N9/12;C12N15/09;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/573;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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