发明名称 Alpha-glucosidase inhibitors and their synthesis from a natural source
摘要 The present invention provides novel alpha-glucosidase inhibitory compound (-)-mesquitol and its analogs isolated in significant yield from traditional medicinal plant Dichrostachys cinerea and further modification of (-)-mesquitol to enhance the alpha- glucosidase inhibitory potential; the invention also identifies the usage of (-)-mesquitol and its analogues, based on their alpha-glucosidase inhibitory activity, as broad based potential therapeutics as antihyperglycernic, antidiabatic, antiobesity, antiviral, anticancer, immunestimulants and the like.
申请公布号 US2004171674(A1) 申请公布日期 2004.09.02
申请号 US20030403034 申请日期 2003.04.01
申请人 COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEA 发明人 RAO JANASWAMY MADHUSUDANA;RAO RAO JAGADEESHWAR;KUMAR UPPARAPALLI SAMPATH;REDDY SINGIREDDY VENKAT;TIWARI ASHOK KUMAR;YADAV JHILLUSINGH;RAGHAVAN KONDAPURAM VIJAYA
分类号 A61K31/353;C07D311/64;(IPC1-7):A61K31/353;C07D311/74 主分类号 A61K31/353
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