发明名称 Gem-disubstituted cyclohexane derivatives and their use as therapeutic agents
摘要 The present invention relates compounds of the formula (I): wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<8>, R<9 >and R<10 >represent a variety of substituents, ring A is a phenyl or pyridyl ring; d is zero, 1 or 2; and pharmaceutically acceptable salts and N-oxides thereof. The compounds are of particular use in the treatment or prevention of depression, anxiety, pain, inflammation, migraine, emesis or postherpetic neuralgia.
申请公布号 US2004171642(A1) 申请公布日期 2004.09.02
申请号 US20030481477 申请日期 2003.12.17
申请人 PINEIRO JOSE LUIS CASTRO;DINNELL KEVIN;ELLIOTT JASON MATTHEW;HOLLINGWORTH GREGORY JOHN;SHAW DUNCAN EDWARD;SWAIN CHRISTOPHER JOHN 发明人 PINEIRO JOSE LUIS CASTRO;DINNELL KEVIN;ELLIOTT JASON MATTHEW;HOLLINGWORTH GREGORY JOHN;SHAW DUNCAN EDWARD;SWAIN CHRISTOPHER JOHN
分类号 C07D207/26;C07D211/76;C07D241/08;C07D405/04;C07D491/10;(IPC1-7):A61K31/454;A61K31/443;A61K31/401;C0741/02 主分类号 C07D207/26
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