摘要 |
This invention provides device for co-culturing at least two different cell types in a two-dimensional configuration, methods of patterning at least two different cell types in a two-dimensional co-culture configuration, and uses of these devices and methods for analyzing an effect of candidate compound on such cellular co-cultures. Also provided is a transmigration and extravasation device. Assay devices for analyzing the absorption, permeability, metabolism and/or toxicity of a candidate compound by a cell are provided. A microfluidic network, which is adaptable for integration with a device for coculturing is provided. |
申请人 |
SURFACE LOGIX, INC.;CAMPBELL, STUART;KIM, ENOCH;KIRK, GREGORY, L.;OSTUNI, EMANUELE;SCHUELLER, OLIVIER;CASAGRANDE, ROCCO;WANG, EVELYN;SWEETNAM, PAUL |
发明人 |
CAMPBELL, STUART;KIM, ENOCH;KIRK, GREGORY, L.;OSTUNI, EMANUELE;SCHUELLER, OLIVIER;CASAGRANDE, ROCCO;WANG, EVELYN;SWEETNAM, PAUL |