发明名称 |
Cytotoxic T-Lymphocyte antigen-4 or interleukin-10 polymorphisms as predictors of response to therapeutic intervention |
摘要 |
A composition and process are provided for predicting the responsiveness of an individual to therapy for a pathological condition is based on detecting nucleic acid allele sequences in an interleukin-10 regulatory region or cytotoxic t-lymphocyte antigen-4 promoter or exon region of the individual. The detected nucleic acid allele is then associated with the level of therapeutic responsiveness to a pathological condition based upon genotype. Comparison across multiple alleles and regions improves the predictive nature of the process.
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申请公布号 |
US2004170996(A1) |
申请公布日期 |
2004.09.02 |
申请号 |
US20040469277 |
申请日期 |
2004.02.25 |
申请人 |
YEE LELAND;TANG JIANMING;KASLOW RICHARD A.;VAN LEEUWEN DIRK J. |
发明人 |
YEE LELAND;TANG JIANMING;KASLOW RICHARD A.;VAN LEEUWEN DIRK J. |
分类号 |
C12Q1/68;C12Q1/70;(IPC1-7):C12Q1/70 |
主分类号 |
C12Q1/68 |
代理机构 |
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