Implant body having a multiblock copolymer coating

摘要

An implant with a form-stable carrier comprising a polyglycolic acid optionally admixed with a further biodegradable polymer is coated with a multiblock copolymer layer. An implant with a form-stable carrier comprising a polyglycolic acid optionally admixed with a further biodegradable polymer is coated with a multiblock copolymer layer, and is such that the multiblock copolymer has >=2 chemically different blocks obtained by linear polycondensation of an alpha ,omega -dihydroxypolyester (I) with a diisocyanate, (I) being obtained by transesterification of poly-(R)- 3-hydroxybutyric acid (and/or its copolymers with 3- hydroxyvaleric acid) with ethyleneglycol, and the linear polycondensation involving either a further alpha ,omega -dihydroxypolyester or an alpha ,omega -dihydroxypolyether comprising alpha ,omega -dihydroxypoly(oxytetramethylene), alpha ,omega - dihydroxypoly(oxyethylene) or copolymers of ethyleneglycol and propyleneglycol. An independent claim is also included for production of the implant by coating the carrier, followed by applying and cell colonizing a connective tissue layer on the multiblock copolymer layer and then applying and cell colonizing an endothelial layer on the connective tissue layer.