发明名称 |
Modifying tissue surfaces by liquid crystal formation |
摘要 |
A method for modifying the surface properties of tissue in vivo is described. The method comprises forming a liquid crystalline matrix on the tissue surface wherein the matrix comprises a tissue surface component. In one embodiment there is provided a method for improving the bonding of surgical glues and cements to cartilage and other synovial fluid wetted tissue surfaces. Such surfaces are contacted with a composition comprising a poly(hydroxy substituted amino acid) to form a liquid crystalline matrix on the tissue surface. The matrix is readily removed to provide a tissue surface that exhibits improved bonding with surgical glues.
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申请公布号 |
US6784282(B2) |
申请公布日期 |
2004.08.31 |
申请号 |
US20020188426 |
申请日期 |
2002.07.02 |
申请人 |
HWANG JULIA;STUPP SAMUEL I. |
发明人 |
HWANG JULIA;STUPP SAMUEL I. |
分类号 |
A61B17/00;A61B17/56;A61F2/00;A61F2/02;A61F2/30;A61L24/00;A61L27/26;A61L27/34;A61L27/50;A61L31/00;(IPC1-7):A61B19/00;A61K38/00;C07K14/00 |
主分类号 |
A61B17/00 |
代理机构 |
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