| 摘要 |
An continuous dry powder inhaler arrangement is disclosed, the arrangement being provided with electrostatically dosed medical powder onto an exchangeable dosing member like a cassette or the like for respiratory administration of medicaments into the deep or upper lung airways. The inhaler presents a compact integrated device (8) with a case having a sliding lid (17), which can be set in an open position exposing a mouthpiece (19) or in a closed position. The arrangement further provides dose (18b/18c) counters and a cassette counter (34). In the state with open lid (17) the device is ready to deliver a prepared pre-metered dose of medical powder upon an inhalation via the exposed mouthpiece (19). Medical drugs are in advance dosed as medical powder and carried by an exchangeable dosing means and constitute dry powder substances or dry powder medical formulations prepared for continuous dosing during a preset period of operation. The exchangeable dosing member carries a number of sequentially accessible doses, which are sealed to preserve a controlled storing of powder during the total lifetime of the dosing member. The sealing is cut open during an inhalation process after that the device has been set into the open state by moving the sliding lid (17) to the open position. Upon an inhalation the cassette carrying a selected dose is released into a longitudinal motion by a forcing spring, whereby the protective foil is cut open to let a nozzle of a suction tube access the powder. By means of a braking arrangement the motion of the cassette is adjusted to such a speed that the time for a continuous delivery of the powder will be prolonged to an order of 1 to 2 seconds. The exchangeable dosing means presents a number of electrostatically deposited dry medical powder. |
