发明名称 Benzodiazepine (BZP) receptor inverse agonists for the prevention and treatment of alzheimer's disease and schizophrenia
摘要 The compound of formula (I) is used in the manufacture of a medicament for the prevention and treatment of schizophrenia wherein: Het is an oxadiazolyl group; R1 is H, lower alkyl, cyclo-lower alkyl, trifluromethyl group, lower alkenyl, lower alkynyl, lower alkoxy group, lower alkoxy-lower alkyl group, hydroxy-lower alkyl group, or an optionally substituted aryl or heteroaryl group; R2 is H, lower alkyl group, cyclo-lower alkyl group, cyclo-lower alkylmethyl group, lower alkenyl group, cyclo-lower alkenyl group, lower alkynyl group, optionally substituted aryl or heteroaryl group.
申请公布号 NZ523189(A) 申请公布日期 2004.08.27
申请号 NZ20010523189 申请日期 2001.06.12
申请人 DAINIPPON PHARMACEUTICAL CO 发明人 FURUKAWA, KIYOSHI;KURUMIYA, SATOSHI;OHNO, KAZUNORI;OKIMOTO, KAZUO
分类号 A61K31/4245;A61K31/4375;A61K31/444;A61P25/00;A61P25/18;A61P25/28;C07D471/04;(IPC1-7):C07D471/04;A61K31/437 主分类号 A61K31/4245
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