发明名称 Sustained release of microcrystalline peptide suspensions.
摘要 The invention relates to a method of preventing gel formation of a hydrophobic peptides by contacting the hydrophobic peptide with a counter-ion in an amount and at a molar ratio sufficient to provide a fluid, milky microcrystalline aqueous suspension of the peptide without formation of a gel. The invention also relates to a fluid, milky microcrystalline aqueous suspension of a hydrophobic peptide and a counter-ion in water, wherein the peptide and counter-ion are present in amounts and at a molar ratio sufficient to form, upon mixing, the suspension without formation of a gel.
申请公布号 ZA200401390(B) 申请公布日期 2004.08.27
申请号 ZA20040001390 申请日期 2004.02.20
申请人 ZENTARIS GMBH. 发明人 ROMANO DEGHENGHI;FRANCOIS BOUTIGNON
分类号 A61K9/10;A61K9/00;A61K9/19;A61K9/22;A61K38/04;A61K38/09;A61K38/31;A61K47/02;A61K47/10;A61K47/12;A61K47/20;A61K47/26;A61P43/00 主分类号 A61K9/10
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