发明名称 Adenovirus formulations
摘要 The invention relates to viral formulations and related pharmaceutical products for use in gene therapy and/or vaccine applications. Especially preferred viral formulations disclosed herein are liquid adenovirus formulations, which show improved stability when stored in about the 2-8° C. range while also being compatible with parenteral administration. These formulations comprise a buffer, a sugar, a salt, a divalent cation, a non-ionic detergent, as well as a free radical scavenger and/or a chelating agent to inhibit free radical oxidation.
申请公布号 US2004166122(A1) 申请公布日期 2004.08.26
申请号 US20040791503 申请日期 2004.03.02
申请人 EVANS ROBERT K.;VOLKIN DAVID B. 发明人 EVANS ROBERT K.;VOLKIN DAVID B.
分类号 A61K9/08;A61K9/00;A61K35/76;A61K39/235;A61K47/00;A61K47/02;A61K47/10;A61K47/18;A61K47/26;A61K47/34;A61K47/46;A61K48/00;A61P31/12;A61P43/00;(IPC1-7):A61K39/12 主分类号 A61K9/08
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