| 摘要 |
1. A method of gradually reducing or eliminating an individual's tobacco usage habit, comprising the step: (a) administering an alternative nicotine source in the form of a transdermal patch comprising a nicotine substance once a day for a predetermined period of time, wherein the predetermined period of time the individual continues to use tobacco but significantly reduces tobacco usage; (b) administering a second alternative nicotine source in the form of a transdermal patch comprising a nicotine substance once a day for a second predetermined period of time, wherein the second predetermined period of time the individual uses no tobacco; wherein second alternative nicotine source comprises a higher nicotine substance dosage than the first alternative nicotine source. 2. The method of claim 1 wherein the first predetermined period of time is substantially 2 to 3 weeks in length. 3 The method of claim 1 wherein the first predetermined period of time the individual reduces tobacco usage by about 33% or more. 4. The method of claim 1 wherein the first predetermined period of time the individual reduces tobacco usage by about 50% or more. 5. The method of claim 1 wherein the first predetermined period of time the individual reduces tobacco usage by about 67% or more. 6. The method of claim 1 or 2 wherein step (a) comprises two or more predetermined periods of time wherein the nicotine substance dosage in the alternative nicotine source and/or the reduction in tobacco usage is varied between the predetermined periods of time. 7. The method of claim 9 wherein step (a) comprises (a) two predetermined periods of time wherein a first such period tobacco usage is reduced by about 50% and the transdermal patch comprises about 14 mg nicotine dosage, and wherein the second such period the new level of tobacco usage is maintained or further reduced and the transdermal patch comprises about 14 mg nicotine dosage; or (b) three predetermined periods of time wherein a first such period tobacco usage is reduced by about 33% and the transdermal patch comprises about 7 mg nicotine dosage, wherein the second such period tobacco usage is reduced by about 67% and the transdermal patch comprises about 14 mg nicotine dosage, and wherein the third such period tobacco usage is maintained at the new level or further reduced and the transdermal patch comprises about 14 mg nicotine dosage. 8. A method of any of the preceding claims wherein the nicotine substance is nicotine. 9. A method of gradually reducing or eliminating an individual's tobacco usage habit, comprising the steps of: (a) administering a first alternative nicotine source in the form of a transdermal patch comprising a nicotine substance once a day for a first predetermined period of time, wherein the first predetermined period of time the individual significantly reduces tobacco usage; (b) administering the first alternative nicotine source once a day for a second predetermined period of time, wherein the second predetermined period of time the individual further reduces tobacco usage; (c) administering a second alternative nicotine source in the form of a transdermal patch comprising a nicotine substance once a day for a third predetermined period of time, wherein the second alternative nicotine source comprises a higher nicotine substance dosage than the first alternative nicotine source; (d) administering a third alternative nicotine source in the form of a transdermal patch comprising a nicotine substance once a day for a fourth predetermined period of time, wherein the third alternative nicotine source comprises substantially the same nicotine substance dosage as the first alternative nicotine source; and (e) administering a fourth alternative nicotine source in the form of a transdermal patch comprising a nicotine substance once a day for a fifth predetermined period of time, wherein the fourth alternative nicotine source comprises a lower nicotine substance dosage than the first alternative nicotine source; wherein during the third, fourth and fifth predetermined periods of time the individual uses no tobacco. 10. A method according to claim 9 wherein the nicotine substance in steps (a) (e) is nicotine. 11. A method according to claim 10 wherein: the first transdermal patch comprises about 14 mg nicotine dosage, the second transdermal patch comprises about 21 mg nicotine dosage, the third transdermal patch comprises about 14 mg nicotine dosage, and the fourth transdermal patch comprises about 7 mg nicotine dosage. 12. A method according to any of claims 9-11 wherein: the first predetermined period of time is substantially 1 week in length; the second predetermined period of time is substantially 1 week in length; the third predetermined period of time is substantially 6 weeks in length; the fourth predetermined period of time is substantially 2 weeks in length; and the fifth predetermined period of time is substantially 2 weeks in length. 13. A method according to any of claims 9-12 wherein during the first to the fifth predetermined periods of time the individual addresses the social and psychological reasons for smoking. 14. A method according to any of claims 9-13 wherein during the first predetermined period of time, the individual reduces tobacco use by about 33% or more. 15. A method according to any of claims 9-13 wherein during the first predetermined period of time, the individual reduces tobacco use by about 50% or more. 16. A method according to any of the claims 9-13 wherein during the second predetermined period of time, the individual reduces tobacco use by about 66% or more. 17. A method according to any of the preceding claims in which the tobacco usage is smoking. 18. A method according to any of the preceding claims in which the tobacco usage is the use of a form of smokeless tobacco.
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