发明名称 |
A GENOMIC APPROACH TO IDENTIFICATION OF NOVEL BROAD-SPECTRUM ANTIMICROBIAL PEPTIDES FROM BONY FISH |
摘要 |
There is provided a method of identifying candidate nucleic acid sequences encoding antimicrobial peptides. The method comprises: identifying an initial peptide of interest; identifying genomic DNA encoding the initial peptide; identifying a flanking sequence on each side of the initial peptide; obtaining primers complementary to the flanking sequences; and, screening a wide range of nucleic acid sequences to identify candidate sequences capable of being amplified using the primers from step e). In some instances the antimicrobial peptide is a hepcidin or a pleurocidin. |
申请公布号 |
WO2004018706(A3) |
申请公布日期 |
2004.08.26 |
申请号 |
WO2003CA01323 |
申请日期 |
2003.08.22 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA;DOUGLAS, SUSAN;GALLANT, JEFFREY;PATRZYKAT, ALEKSANDER |
发明人 |
DOUGLAS, SUSAN;GALLANT, JEFFREY;PATRZYKAT, ALEKSANDER |
分类号 |
C12N15/09;A61K38/00;C07K7/06;C07K7/08;C07K14/46;C12N15/10;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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