| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for identifying potential herbicides. SOLUTION: This method for identifying potential herbicides comprises testing a compound in an AMP (adenosine monophosphate) deaminase inhibition assay and, if a measurable reduction of AMP deaminase is observed, subsequently subjecting the compound to conventional test(s) to confirm the in vivo herbicidal activity, wherein the measurable reduction is at least 25% reduction of AMP deaminase when tested against an enzyme preparation at 100μM or less. The method for identifying the potential herbicides that can be metabolized to an inhibitor against AMP deaminase inside a plant comprises testing a compound in an adenosine deaminase inhibition assay and, if a measurable reduction of adenosine deaminase is observed, subsequently subjecting the compound to conventional test(s) to confirm the in vivo herbicidal activity, wherein the measurable reduction is at least 25% reduction of adenosine deaminase when tested against an enzyme preparation at 100μM or less. COPYRIGHT: (C)2004,JPO&NCIPI
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