发明名称 A DEVICE AND METHOD FOR THE DETERMINATION OF LITHIUM ION CONCENTRATION IN A BIOLOGICAL FLUID
摘要 The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said compound for the detection of lithium ions. Additionally, the present invention provides a method of detecting lithium ions which comprises placing the novel optical sensor into communication with a biological fluid. Once the novel compound of the present invention encounters a lithium ion(s), a fluorescence is generated, the intensity of which is measured and allows for the determination of lithium ion concentration. The present invention provides a medical professional with the ability to selectively determine lithium ion concentration in a biological fluid thereby facilitating the treatment of various diseases, such as manic-depressive illness.
申请公布号 WO2004071345(A2) 申请公布日期 2004.08.26
申请号 WO2004US04053 申请日期 2004.02.12
申请人 BAYER HEALTHCARE LLC;WORCESTER POLYTECHNIC INSTITUTE;BENCO, JOHN, S.;NIENABER, HUBERT, A.;MCGIMPSEY, W., GRANT 发明人 BENCO, JOHN, S.;NIENABER, HUBERT, A.;MCGIMPSEY, W., GRANT
分类号 C07D273/01;C07D498/08;G01N21/64;G01N21/77;G01N31/22;G01N33/84 主分类号 C07D273/01
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