| 发明名称 |
Process for the preparation of (E)-5-(2-bromovinyl)-29-deoxyuridine. |
| 摘要 |
Process of preparing (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvent selected form esters or cyclic ethers are used in the bromination step of 5-ethyl-2'-deoxyuridine diacylate. The use of solvents is advantageous in respect of toxicity, discharge costs and environment protection. |
| 申请公布号 |
ZA200306639(B) |
申请公布日期 |
2004.08.26 |
| 申请号 |
ZA20030006639 |
申请日期 |
2003.08.26 |
| 申请人 |
MENARINI RICERCHE S.P.A. |
发明人 |
ALDO SALIMBENI;CARLO ALBERTO MAGGI;STEFANO MANZINI;DAMIANO TUROZZI |
| 分类号 |
C07H19/073;C07B61/00;C07H19/06 |
主分类号 |
C07H19/073 |
| 代理机构 |
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