| 摘要 |
A continuous simulated moving bed chromatographic focusing process is disclosed for separating and concentrating multiple components from a complex mixture. Said process comprises a number of zones that are connected in series. An eluent flows unidirectionally along the zones and decreases its desorption strength by sequential dilutions zone after zone. Each zone is detachably installed with a chromatographic column and the columns are periodically relocated one zone upstream. Multiple components of a sample are introduced into a downstream zone, absorbed on the column in the zone, brought zone by zone upstream by column relocations, and selectively desorbed from different zones to get separations. A component desorbed from one zone is reabsorbed by the column in the adjacent downstream zone and is again brought back to said zone by column relocation said component is thus retained between said zone and said adjacent downstream zone and is accumulated by continuous sample feeding and repeatedly column relocation. |
