发明名称 |
Use of estrogen receptor alpha modulators for the treatment of multiple sclerosis |
摘要 |
The present invention provides methods of treating an autoimmune pathology in a mammal, comprising administering an agent with estrogen receptor alpha agonist activity in particular a selective estrogen receptor modulator, to the mammal in an amount sufficient to decrease production of TH-1 and/or TH-2 cytokines. Also provided is a method of selecting compounds useful for the treatment of multiple sclerosis, comprising selecting a compound which has estrogen receptor alpha agonist activity.
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申请公布号 |
US2004167112(A1) |
申请公布日期 |
2004.08.26 |
申请号 |
US20040751543 |
申请日期 |
2004.01.05 |
申请人 |
WYETH |
发明人 |
ELLOSO M. MERLE;MITCHELL ROBERT;HARNISH DOUGLAS C.;ADELMAN STEVEN J. |
分类号 |
A61K31/00;A61K31/137;A61K31/138;A61K31/40;A61K31/4535;A61K31/55;A61K31/56;A61P37/00;A61P37/06;(IPC1-7):A61K31/56 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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