发明名称 |
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH ACETYLCHOLINE RECEPTOR, MUSCARINIC 4(M4) |
摘要 |
The invention provides a human M4 which is associated with the disorders of the gastroenterology system, disorders of the peripheral and central nervous system, hematology diseases, cardiovascular diseases, repiratory diseases and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of disorders of the gastroenterology system, disorders of the peripheral and central nervous system, hematology diseases, cardiovascular diseases, repiratory diseases and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of M4 as well as pharmaceutical compositions comprising such compounds. |
申请公布号 |
WO2004071392(A2) |
申请公布日期 |
2004.08.26 |
申请号 |
WO2004EP00784 |
申请日期 |
2004.01.29 |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;SUMMER, HOLGER |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;SUMMER, HOLGER |
分类号 |
A61K38/17;A61P1/00;A61P7/00;A61P9/00;A61P11/00;A61P25/00;A61P29/00;G01N33/74 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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