| 发明名称 |
Novel Pyrimidine-4,6-dicarboxylic acid diamides for selectively inhibiting collagenases |
| 摘要 |
Pyrimidine-4,6-dicarboxylic acid diamides of the formula I are suitable for selectively inhibiting collagenase (MMP 13). The pyrimidine-4,6-dicarboxylic acid diamides can therefore be used for treating degenerative joint diseases.
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| 申请公布号 |
US2004167120(A1) |
申请公布日期 |
2004.08.26 |
| 申请号 |
US20030700273 |
申请日期 |
2003.11.03 |
| 申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
KLINGLER OTMAR;KIRSCH REINHARD;HABERMANN JOERG;WEITHMANN KLAUS-ULRICH;ENGEL CHRISTIAN;PIRARD BERNARD |
| 分类号 |
C07D239/28;C07D401/12;C07D403/12;C07D405/12;C07D405/14;C07D409/14;C07D413/12;C07D413/14;C07D471/04;(IPC1-7):A61K31/55;A61K31/506;C0743/02 |
主分类号 |
C07D239/28 |
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