发明名称 DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS
摘要 <p>A compound having the structure: wherein (a) n is from about 1 to about 3; (b) X is selected from the group consisting of O, S, SO, or SO2; (c) Y is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 carbon atoms, or the Y's are bonded together to form an alkanyl ring having from about 3 to about 7 atoms; (d) Z is hydrogen or straight, branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; and (e) Het is a heteroaryl group comprising one or more rings each ring containing from about 5 to about 6 atoms other than hydrogen and wherein the group contains at least one heteroatom selected from O, N, or S. pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.</p>
申请公布号 EP0883616(B1) 申请公布日期 2004.08.25
申请号 EP19970904018 申请日期 1997.01.30
申请人 VANDERBILT UNIVERSITY 发明人 WU, LAURENCE, ICHIH;JANUSZ, JOHN, MICHAEL
分类号 C07D333/54;A61K31/34;A61K31/343;A61K31/38;A61K31/381;A61K31/382;A61K31/415;A61K31/425;A61K31/427;A61K31/44;A61P29/00;A61P43/00;C07D307/79;C07D335/06;C07D337/08;C07D409/04;C07D417/04;C07D471/04;C07D513/04;(IPC1-7):C07D307/79 主分类号 C07D333/54
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