发明名称 Aryl and aminoaryl substituted serotonin receptor agonist and antagonist ligands
摘要 The present invention is directed to certain novel compounds represented by structural Formula (I):or a pharmaceutically acceptable salt thereof, wherein S<ag >and T<ag >are described herein. The invention is also concerned with pharmaceutical formulations comprising these novel compounds as active ingredients and the use of the novel compounds and their formulations in the treatment of certain disorders. The compounds of this invention are serotonin agonists and antagonists and are useful in the control or prevention of central nervous system disorders including obesity, anxiety, depression, psychosis, schizophrenia, sleep and sexual disorders, migraine and other conditions associated with cephalic pain, social phobias, and gastrointestinal disorders such as dysfunction of the gastrointestinal tract motility.
申请公布号 US6780862(B2) 申请公布日期 2004.08.24
申请号 US20010026226 申请日期 2001.12.19
申请人 BRISTOL-MYERS SQUIBB PHARMA COMPANY 发明人 ROBICHAUD ALBERT J.;MITCHELL IAN S.
分类号 A61K31/343;A61K31/4035;A61K31/404;A61K31/407;A61K31/416;A61K31/437;A61K31/473;A61K31/4985;A61K31/55;A61P1/06;A61P3/04;A61P15/00;A61P25/06;A61P25/24;A61P25/28;A61P43/00;C07D209/04;C07D209/08;C07D209/14;C07D209/62;C07D221/10;C07D231/54;C07D231/56;C07D307/85;C07D471/04;C07D487/04;(IPC1-7):C07D241/36;A61K31/498 主分类号 A61K31/343
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