Chiral lead catalyst and method of asymmetric aldol reaction

摘要

A novel chiral lead catalyst comprising a lead compound of the following formula:(wherein Rf represents a fluorine-containing alkylsulfonyl group)and a chiral crown ether compound having the structure of the following formula:which is applicable in a variety of reactions, and enables simple reaction operations with high yield and high optical selectivity, is provided. Also provided is a method of asymmetric synthesis using the same.