发明名称 |
PROCESS FOR THE FERMENTATIVE PREPARATION OF L-AMINO ACIDS WITH AMPLIFICATION OF THE GND GENE |
摘要 |
The invention relates to a process for the preparation of L-amino acids. The process involves fermenting an L-amino acid producing coryneform bacteria in a culture medium, concentrating L-amino acid produced by the fermenting in the culture medium or in the cells of the bacteria, and isolating the L-amino acid produced. The bacteria has an overexpressed gene encoding 6-phosphogluconate dehydrogenase and a decreased or switched off gene encoding pyruvate oxidase. The L-amino acid may be L-lysine, L-threonine, L-isoleucine or L-tryptophan. |
申请公布号 |
PL358912(A1) |
申请公布日期 |
2004.08.23 |
申请号 |
PL20000358912 |
申请日期 |
2000.07.05 |
申请人 |
DEGUSSA AG;NATIONAL UNIVERSITY OF IRELAND |
发明人 |
DUNICAN L.K.;MCCORMACK ASHLING;STAPELTON CLIONA;BURKE KEVIN;MOCKEL BETTINA |
分类号 |
C12N1/21;C12N9/02;C12N15/53;C12N15/77;C12P13/08 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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