APPLICATION OF ANTIPROGESTAGENS IN COMBINED THERAPY

摘要

FIELD: medicine, gynecology. ^ SUBSTANCE: invention can be used in carrying out contraception or substitution hormonal therapy in women. For this purpose in schedules suggesting the participation of an antiprogestagen the invention proposes application of Org 33245 as an antiprogestagen that is administrated in discontinuous regimen when a break between each pair of sequentially administrated standard doses is more 1 day. Invention provides minimization of uterine bleeding in combination with high activity and selectivity of antiprogestin effect. ^ EFFECT: enhanced effectiveness of therapy. ^ 9 cl, 1 tbl, 4 ex