| 摘要 |
The invention relates to 5-HT receptor agonists or antagonists. Novel arylpiperazinyl sulfonamide compounds represented by formula (I), and synthesis and uses thereof for treating diseases including those mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as generalized anxiety disorder, ADD/ADHD, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included. |
| 申请人 |
PREDIX PHARMACEUTICALS HOLDINGS, INC.;DHANOA, DALE, S.;CHEN, DONGLI;BECKER, OREN;NOIMAN, SILVIA;CHERUKU, SRINIVASA, RAO;MARANTZ, YAEL;SHARADENDU, ANURAG;SHACHEM, SHARON;HEIFETZ, ALEXANDER;MOHANTY, PRADYUMNA;INBAL, BOAZ;FICHMAN, MERAV;NUDELMAN, RAPHAEL;BAR-HAIM, SHAY |
发明人 |
DHANOA, DALE, S.;CHEN, DONGLI;BECKER, OREN;NOIMAN, SILVIA;CHERUKU, SRINIVASA, RAO;MARANTZ, YAEL;SHARADENDU, ANURAG;SHACHEM, SHARON;HEIFETZ, ALEXANDER;MOHANTY, PRADYUMNA;INBAL, BOAZ;FICHMAN, MERAV;NUDELMAN, RAPHAEL;BAR-HAIM, SHAY |
