发明名称 |
ISG15-CONJUGATED PROTEINS |
摘要 |
The present invention provides methods to identify ISG15 target proteins, methods to identify compounds that alter the conjugation of ISG15 with target proteins, methods for altering the level of ISG15-conjugated protein in a patient or a sample, methods to diagnose a patient having a malcondition characterized by an altered level of ISG15-conjugated protein, ISG15-conjugates, methods to treat cancer by promoting conjugation of a target protein to ISG15, and antibodies that selectively bind to ISG15-conjugates. |
申请公布号 |
WO2004069860(A2) |
申请公布日期 |
2004.08.19 |
申请号 |
WO2004US02966 |
申请日期 |
2004.02.03 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE;ZHANG, DONG-ER;MALAKHOV, MIKHAIL, P.;MALAKHOVA, OXANA, A. |
发明人 |
ZHANG, DONG-ER;MALAKHOV, MIKHAIL, P.;MALAKHOVA, OXANA, A. |
分类号 |
A61K38/16;A61K39/385;C07K;C07K16/18;C07K16/44;G01N33/53;G01N33/536;G01N33/543;G01N33/561;G01N33/577;G01N33/68 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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