摘要 |
The invention provides methods and compositions for treatment of bacterial infections. Methods of the invention include administration of dalbavancin for treatment of a bacterial infection, in particular a Gram-positive bacterial infection of skin and soft tissue, under conditions where a protein-dalbavancin complex forms, or administering a protein-dalbavancin complex. Dosing regimes include once weekly administration of dalbavancin, which often remains at therapeutic levels in the bloodstream for at least one week, providing prolonged therapeutic action against a bacterial infection. |
申请人 |
VICURON PHARMACEUTICALS INC.;CAVALERI, MARCO;COLOMBO, LUIGI;HENKEL, TIMOTHY;JABES, DANIELA;MALABARBA, ADRIANO;MOSCONI, GIORGIO;STOGNIEW, MARTIN;WHITE, RICHARD, J. |
发明人 |
CAVALERI, MARCO;COLOMBO, LUIGI;HENKEL, TIMOTHY;JABES, DANIELA;MALABARBA, ADRIANO;MOSCONI, GIORGIO;STOGNIEW, MARTIN;WHITE, RICHARD, J. |