发明名称 |
3R-3'R Diastereoisomer von Zeaxanthin zur Behandlung von der Degeneration der Macula |
摘要 |
Methods and formulations are disclosed for making and purifying the 3R-3'R stereoisomer of zeaxanthin as a sole detectable isomer, in any desired quantity, for use as a drug or vitamin by humans. Zeaxanthin preparations which contain only the desired 3R-3'R stereoisomer can be produced by a strain of Flavobacterium multivorum bacterial cells (ATCC accession number 55238). These cells (and other cells transformed with their zeaxanthin-producing genes) do not create any detectable quantities of the undesired S-S or S-R isomers of zeaxanthin. The pure R-R isomer can be taken orally, either as a therapeutic drug by patients suffering from macular degeneration, or as a vitamin or nutritional supplement to reduce the risk of age-related macular degeneration. |
申请公布号 |
DE69632898(D1) |
申请公布日期 |
2004.08.19 |
申请号 |
DE1996632898 |
申请日期 |
1996.10.31 |
申请人 |
ZEAVISION L.L.C., CHESTERFIELD |
发明人 |
GARNETT, KEVIN M.;GIERHART, DENNIS L.;GUERRA-SANTOS, LUIS H. |
分类号 |
A23L1/30;A61K9/107;A61K9/48;A61K31/045;A61K31/047;A61P27/02 |
主分类号 |
A23L1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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