发明名称 |
Dye-azide compounds for dual phototherapy |
摘要 |
The present invention discloses dye-azide derivatives and their bioconjugates for dual phototherapy of tumors and other lesions. The compounds of the present invention may contain either a mixture of Type 1 and Type 2 agents or a single entity that integrates both units in the same molecules. The compounds are designed to produce both Type 1 and Type 2 phototherapeutic effect at once using dual wavelength light source that will produce singlet oxygen and nitrene at the lesion of interest.
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申请公布号 |
US2004161430(A1) |
申请公布日期 |
2004.08.19 |
申请号 |
US20040776840 |
申请日期 |
2004.02.11 |
申请人 |
MALLINCKRODT INC. |
发明人 |
RAJAGOPALAN RAGHAVAN;ACHILEFU SAMUEL I.;BUGAI JOSEPH E.;DORSHOW RICHARD B. |
分类号 |
C07D277/64;A61K31/409;A61K31/428;A61K41/00;A61K45/00;A61K47/48;A61P9/10;A61P35/00;A61P43/00;C07D487/22;C09B47/04;(IPC1-7):A61K39/395 |
主分类号 |
C07D277/64 |
代理机构 |
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代理人 |
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地址 |
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