| 摘要 |
<p>A carboxylic acid compound represented by the following general formula (I), its pharmaceutically acceptable salt, a process for producing the same and a drug containing the same as the active ingredient: (I) wherein R<1> represents H or alkyl; m is 2 or 3; n is an integer of from 0 to 2; R<2> represents phenyl, naphthyl, benzofuran or benzothiophene; Q represents -CH2-O-Cyc1, -CH2-Cyc2 or -L-Cyc3; and R<3a> and R<3b> independently represent each hydrogen or alkyl, or R<3a> and R<3b> represent together tetrahydro-2H-pyrane. Because of having antagonism specifically to PGE2 receptors (in particular, EP3 receptor which is one of the subtypes thereof), compounds represented by the general formula (I) are useful in preventing and/or treating itching, pain, urinary disorder or stress-induced diseases.</p> |
