| 摘要 |
PURPOSE: A probe medium and a method of producing the same probe medium are provided, thereby effectively and stably immobilizing a probe on the substrate, and simplifying the probe medium production process and reducing the production time. CONSTITUTION: The probe medium comprises a probe capable of specifically binding to a target substance; a medium containing an organic solvent; and a substance for solubilizing the probe in the organic solvent, wherein the probe is a nucleic acid probe; the organic solvent is a solvent in which the probe is insoluble; the substance for solubilizing the probe in the organic solvent is an amphipathic substance; and the substance for solubilizing the probe in the organic solvent is a substance selected from the group consisting of n-hexadecyl trimethyl ammonium bromide, n-hexadecyl trimethyl ammonium chloride, and cetylpyridinium chloride, or a mixture containing at least a substance selected from the group. The method of producing a probe medium that contains a probe capable of specifically binding to a target substance comprises the steps of: dissolving the probe in a solvent in which the probe is soluble; separating the probe from the solvent by acting on the solvent a substance for solubilizing the probe in an organic solvent; and dissolving the probe in the organic solvent by adding the organic solvent to the probe. |
