| 发明名称 |
Chemically-modified progenipoietin conjugates |
| 摘要 |
<p>The present invention provides a chemically modified Progenipoietins (ProGPs) prepared by binding a water soluble polymer to the protein. The chemically-modified protein according to the present invention may have a much longer lasting neutrophil-increasing activity than that of the un-modified ProGP, enabling reduced dose and scheduling opportunities.</p> |
| 申请公布号 |
CZ20033537(A3) |
申请公布日期 |
2004.08.18 |
| 申请号 |
CZ20030003537 |
申请日期 |
2002.06.14 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
SIEGEL NED R.;FINN RORY F.;HILLS ROBERT L. |
| 分类号 |
A61K47/34;A61K38/00;A61K38/18;A61K38/20;A61K47/48;A61P7/00;A61P7/06;A61P7/08;C07K14/475;C07K14/52;C07K14/705;C12N5/06;(IPC1-7):A61K47/48;C07K14/00 |
主分类号 |
A61K47/34 |
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