NOVEL PROTEIN, ITS DNA AND USE THEREOF

摘要

The present invention provides a novel protein which is useful in preventing/treating pulmonary and breast diseases associated with pulmonary and airway inflammation, a polynucleotide encoding the protein, a method of screening a compound inhibiting the activity of the protein, a compound obtained by the screening method, etc. <??>The protein and polynucleotide of the present invention are useful as diagnostic markers for pulmonary and breast disease associated with pulmonary and airway inflammation, rhinitis and the like. Inhibitors obtained by screening with the use of the protein or the polynucleotide and a neutralizing antibody inhibiting the activity of the protein are usable as agents for the prevention/treatment of, for example, pulmonary and breast diseases associated with pulmonary and airway inflammation such as chronic obstructive pulmonary disease, rhinitis and the like.