发明名称 |
Antibodies to cryptosporidium |
摘要 |
A method of producing IgG1 subclass antibodies reactive to the surface of Crystosporidium oocysts, the method comprising: (a) separating at least a protion of the Cryptosporidium oocyst wall from the internal sporozoites to form an oocyst-wall preparation; (b) treating the separated oocyst-wall preparation so as to obtain an oocyst antigen preparation capable of eliciting a detectable IgG1 immune response in an animal to the surface of the oocyst; (c) immunizing an animal with the oocyst antigen preparation so as to elicit an IgG1 immune response in the animal; and (d) obtaining from the animal IgG1 antibodies reactive to the surface of Cryptosporidium oocysts. IgG1 antibodies reactive to the surface of Cryptosporidium oocysts.
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申请公布号 |
US6777222(B1) |
申请公布日期 |
2004.08.17 |
申请号 |
US20000424048 |
申请日期 |
2000.02.24 |
申请人 |
MACQUARIE RESEARCH LTD.;SYDNEY WATER CORPORATION |
发明人 |
VESEY GRAHAM;WEIR CHRISTOPHER;WILLIAMS KEITH LESLIE;SLADE MARTIN BASIL;VEAL DUNCAN |
分类号 |
C07K16/20;G01N33/569;(IPC1-7):C12N1/10;A61K39/395;A61K39/00 |
主分类号 |
C07K16/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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