Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same

摘要

The present invention is directed to polymeric prodrug transport forms and methods of making and using the same. In one preferred aspect, the prodrugs are of the formula:whereinG is a polymeric residue;Z is one of:and B is a residue of a biologically active amine-containing moiety or a hydroxyl-containing moiety.