PHARMACEUTICAL COMPOSITIONS OF GALLIUM COMPLEXES OF 3-HYDROXY-4-PYRONES

摘要

Disclosed are pharmaceutical compositions that comprise gallium complexes of 3- hydroxy-4-pyrones. These compositions provide enhanced gallium bioavailability particularly when orally administer ed as compared to the gallium bioavailability achieved by use of pharmaceutical compositions containing gallium salts. Compositions included in this invention are useful in providing gallium to humans and other mammals for a wide variety of medical and veterinary applications; including the treatment, prevention, or diagnosis of hypercalcemia, certain cancers, certain disorder s of calcium homeostasis, and certain bone dis- eases including osteoporosis, osteopenia, and Paget's disease.