发明名称 Pharmaceutical uses and synthesis of nicotinamides
摘要 A compound of the formulaand pharmaceutically acceptable salts thereof, wherein R<1 >is selected from (R3)C(=O)-N(R<4>)- and (R<3>)(R<4>)N-C(=O)-; R<2 >is selected from -OR<5 >and -N(R<5>)(R<6>); n is 0, 1, 2 or 3; X is selected from oxygen and sulfur; and R<3>, R<4>, R<5 >and R<6 >are independently selected from hydrogen, alkyl, heteroalkyl, aryl, aryl(akylene), heteroaryl, heteroaryl(alkylene), carbocycle, carbocycle(alkylene), heterocycle, and heterocycle(alkylene); as well as pharmaceutical compositions containing said compound. The compounds and compositions are useful in, for example, the treatment of inflammatory events in an animal subject.
申请公布号 US6777432(B1) 申请公布日期 2004.08.17
申请号 US20020237258 申请日期 2002.09.04
申请人 DARWIN MOLECULAR CORPORATION 发明人 CUTSHALL NEIL S.;JEFFREY SCOTT C.
分类号 C07D213/64;C07D213/75;C07D213/82;(IPC1-7):A61K31/44;C07D213/28 主分类号 C07D213/64
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