| 发明名称 |
Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor |
| 摘要 |
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to naphthol, quinoline and isoquinoline-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
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| 申请公布号 |
US2004157865(A1) |
申请公布日期 |
2004.08.12 |
| 申请号 |
US20030616579 |
申请日期 |
2003.07.10 |
| 申请人 |
CODD ELLEN;DAX SCOTT L.;JETTER MICHELE;MCDONNELL MARK;MCNALLY JAMES J.;YOUNGMAN MARK |
发明人 |
CODD ELLEN;DAX SCOTT L.;JETTER MICHELE;MCDONNELL MARK;MCNALLY JAMES J.;YOUNGMAN MARK |
| 分类号 |
C07C275/28;C07C275/30;C07C275/32;C07D213/40;C07D215/38;C07D217/02;C07D217/22;C07D217/24;C07D235/10;C07D235/14;C07D307/52;C07D333/20;C07D333/58;C07D401/12;C07D409/04;(IPC1-7):A61K31/517;A61K31/47 |
主分类号 |
C07C275/28 |
| 代理机构 |
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