GLIOMA-SPECIFIC TRANSCRIPTION CONTROL NUCLEIC ACIDS

摘要

The invention provides isolated transcription control acids that direct transcription selectively in glioma tumor cells. Such transcription control nucleic acids can be incorporated into expression constructs useful for nucleic acids, including polypeptide-encoding nucleic acids. Selectively inglioma tumor cells. Using such expression constructs, anti tumor molecules (e.g., toxins and antisense molecules) can be made selectively in Glioma tumor cells, and thereby selectively inhivit or stop tumor cell growth and/or division.