| 发明名称 |
TKTS AS MODIFIERS OF THE BETA-CATENIN PATHWAY AND METHODS OFUSE |
| 摘要 |
Human TKT genes are identified as modulators of the beta-catenin pathway, an d thus are therapeutic targets for disorders associated with defective beta- catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of TKT are provid ed.
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| 申请公布号 |
CA2513601(A1) |
申请公布日期 |
2004.08.12 |
| 申请号 |
CA20042513601 |
申请日期 |
2004.01.28 |
| 申请人 |
EXELIXIS INC. |
发明人 |
LICKTEIG, KIM;FRANCIS-LANG, HELEN;VENTURA, RICHARD BENN ABEGANIA;WINTER, CHRISTOPHER G. |
| 分类号 |
C12N9/10;C12Q1/48;(IPC1-7):C12Q1/68;A61K38/00;A61K45/00;A61P35/00;C12Q1/00;C12Q1/02;A61K39/395;G01N33/50;G01N33/53;G01N33/543 |
主分类号 |
C12N9/10 |
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