发明名称 |
NUCLEIC ACIDS AND CORRESPONDING PROTEINS ENTITLED 254P1D6B USEFUL IN TREATMENT AND DETECTION OF CANCER |
摘要 |
A novel gene 254P1D6B and its encoded protein, and variants thereof, are described wherein 254P1D6B exhibits tissue specific expression in normal adu lt tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 254P1D6B provides a diagnostic, prognostic, prophylactic and/o r therapeutic target for cancer. The 254P1D6B gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 254P1D6B can be used in active or passive immunization.
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申请公布号 |
CA2514058(A1) |
申请公布日期 |
2004.08.12 |
申请号 |
CA20042514058 |
申请日期 |
2004.01.23 |
申请人 |
AGENSYS, INC. |
发明人 |
CHALLITA-EID, PIA M.;KANNER, STEVEN B.;RAITANO, ARTHUR B.;PEREZ-VILLAR, JUAN J.;GE, WANGMAO;JAKOBOVITS, AYA |
分类号 |
C07K14/47;(IPC1-7):C12N15/12;A61K39/00;A61K48/00;A61P35/00;A61K38/08;C12N5/12;A61K38/17;A61K39/395;A61K38/46;G01N33/53;G01N33/574;C12Q1/68;A61K31/708;A61K31/713 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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