CONTROLLED RELEASE MODIFYING COMPLEX AND PHARMACEUTICAL COMPOSITIONS THEREOF

摘要

Disclosed is a controlled release modifying complex for solid suitable comprises modifying excipients. The release modifying an auxiliary release thereof, wherein modifying agents effect and ingredient.oral controlled release pharmaceutical for an once-a-day administration. The active pharmaceutical ingredient, compositions composition a release complex and other required pharmaceutically acceptable release modifying complex comprises a primary agent, a secondary release modifying agent and modifying agent or varying combinations said primary, secondary and auxiliary release are present in amounts that synergistically extend the release of active pharmaceutical ingredient.