METHOD FOR IDENTIFYING NOVEL TREATMENTS OF INFLAMMATORY DISEASE IN THE GUT

摘要

Model fish and use thereof for screening for the presence of gut inflammatory disease, especially in zebrafish. Induction of the disease state and visualization of the gastrointestinal tract in living zebrafish. Visualization of the inflammatory state in vivo facilitates screening for compounds that can be used in treatment of inflammatory disease of the gut or genetic mutations that rescue or suppress the disease phenotype.