发明名称 Fluorometric Determination of Analytes with Amine-N-Oxides as Redox-Indicators
摘要 <p>Detecting an analyte in a sample comprising contacting the sample with a detection reagent comprising an amino-substituted 2,1,3-benzoxadiazole N-oxide (I) as a fluorimetric redox indicator, is new. Detecting an analyte in a sample comprises contacting the sample with a detection reagent comprising an amino-substituted 2,1,3-benzoxadiazole N-oxide of formula (I) as a fluorimetric redox indicator. [Image] R 1>, R 2>R, (CH 2CH 2O) mR, COR, COOR or OCOR; R 3>NO 2, CN, R, OR, OCOR, COOR, SR or halo; R : H or 1-4C alkyl optionally substituted with halo, OR, SR, NRR, COOR, CONRR, SO 3R and/or PO(OR) 3; m : 1-20; and n : 1-3. An independent claim is also included for a reagent for detecting an analyte by redox reaction and fluorimetric determination, comprising a compound (I) as redox indicator.</p>
申请公布号 EP1445603(A1) 申请公布日期 2004.08.11
申请号 EP20040002460 申请日期 2004.02.04
申请人 F. HOFFMAN-LA ROCHE AG;ROCHE DIAGNOSTICS GMBH 发明人 HORN, CARINA;HOENES, JOACHIM;SPINKE, JUERGEN
分类号 G01N31/22;C12Q1/26;G01N21/64;(IPC1-7):G01N21/64;G01N21/77 主分类号 G01N31/22
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