| 发明名称 |
PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE |
| 摘要 |
A process for easily producing various optically active chroman derivatives that are useful as pharmaceutical intermediates from inexpensive starting materials is provided. <??>Cyclic hemiacetal (1) obtained from dihydrocoumarin through one step is asymmetrically reduced to produce an optically active halohydrin derivative (3), and the optically active halohydrin derivative (3) is cyclized to produce an optically active chroman derivative (13): <CHEM>
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| 申请公布号 |
EP1445324(A1) |
申请公布日期 |
2004.08.11 |
| 申请号 |
EP20020781744 |
申请日期 |
2002.11.07 |
| 申请人 |
KANEKA CORPORATION |
发明人 |
MITSUDA, M.;TANAKA, T.;YASOHARA, YOSHIHIKO |
| 分类号 |
C07C39/24;C07C303/28;C07C303/30;C07C309/66;C07C309/73;C07D311/20;C07D405/06;C12P7/22;(IPC1-7):C12P17/06;C07D311/58;C12R1/19;C12R1/72;C07M7/00 |
主分类号 |
C07C39/24 |
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