发明名称 |
Sensitizing cells for apoptosis by selectively blocking cytokines |
摘要 |
The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis. <IMAGE> |
申请公布号 |
EP1444989(A1) |
申请公布日期 |
2004.08.11 |
申请号 |
EP20030002603 |
申请日期 |
2003.02.07 |
申请人 |
STASSI, GIORGIO, DR.;TODARO, MATILDE, DR. |
发明人 |
STASSI, GIORGIO, DR.;TODARO, MATILDE, DR. |
分类号 |
A61K38/17;A61K38/19;A61K38/20;A61K39/395;A61K45/00;A61K45/06;A61P35/00;A61P37/06;(IPC1-7):A61K45/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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