发明名称 Substituted alkyldiamines as inhibitors of plasmepsin or related proteases.
摘要 The invention relates to novel compounds which are substituted alkyldiamino derivatives of formula (I). The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more compounds of formula (I) and especially their use as inhibitors of the plasmodium falciparum protease plasmepsin II or related aspartic proteases.
申请公布号 ZA200303564(B) 申请公布日期 2004.08.10
申请号 ZA20030003564 申请日期 2003.05.08
申请人 ACTELION PHARMACEUTICALS LTD. 发明人 CHRISTOPH BOSS;SOLANGE MEYER;THOMAS WELLER;WALTER FISCHLI;SYLVIA RICHARD-BILDSTEIN
分类号 A61K31/137;A61K31/166;A61K31/17;A61K31/222;A61K31/275;A61K31/36;A61K31/4402;A61K31/505;A61K45/06;A61P33/06;A61P43/00;C07C211/27;C07C211/29;C07C217/58;C07C233/78;C07C235/50;C07C255/58;C07C255/60;C07C275/28;C07D213/38;C07D213/40;C07D239/26;C07D317/58 主分类号 A61K31/137
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