| 摘要 |
Compounds of formula (I) in free or salt form, where Ar<1 >is phenyl substituted by one or more halogen atoms, Ar<2 >is phenyl or naphthyl which is unsubstituted or substituted by one or more substituents selected from halogen, cyano, hydroxy, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkoxy or C1-C8-alkoxycarbonyl, R<1 >is hydrogen or C1-C8-alkyl optionally substituted by hydroxy, C1-C8-alkoxy, acyloxy, N(R<2>)R<3>, halogen, carboxy, C1-C8-alkoxycarbonyl, -CON(R<4>)R<5 >or by a monovalent cyclic organic group, R<2 >and R<3 >are each independently hydrogen or C1-C8-alkyl, or R<2 >is hydrogen and R<3 >is acyl or -SO2R<6>, or R<2 >and R<3 >together with the nitrogen atom to which they are attached denote a 5 or 6-membered heterocyclic group, R<4 >and R<5 >are each independently hydrogen or C1-C8-alkyl, or R<4 >and R<5 >together with the nitrogen atom to which they are attached denote a 5 or 6-membered heterocyclic group, R<6 >is C1-C8-alkyl, C1-C8-haloalkyl, or phenyl optionally substituted by C1-C8-alkyl, and n is 1, 2, 3, or 4, with the proviso that when Ar<1 >is p-chlorophenyl and R<1 >is hydrogen, R<2 >is not phenyl or p-nitrophenyl. The compounds are useful as pharmaceuticals. |
