Biosensor, device and method for detecting nucleic acids by means of at least two units for immobilizing nucleic acids

摘要

A device and method for detecting nucleic acids. The device having a biosensor with at least two nucleic acid immobilization units and an electrical detection circuit. In the biosensor, the at least two nucleic acid immobilization units are in this case electrically conductive and electrically insulated from one another. The at least two nucleic acid immobilization units are provided with first nucleic acid molecules acting as scavenger molecules. The first nucleic acid molecules are present as single-stranded molecules and can bind second nucleic acid molecules to be detected. The first single-stranded nucleic acid molecules acting as scavenger molecules are provided with a redox-active label capable of generating a detectable signal. The electrical detection circuit is configured in such a way that it detects the hybridization even of the nucleic acid molecules with the scavenger molecules by means of the label.